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Baloxavir ≥ 98% CAS No:1985605-59-1

Baloxavir Powder,Baloxavir≥98%,1985605-59-1,C24H19F2N3O4S,Baroxavir

Content

Product Introduction

巴洛沙韦主图5

Product Name: Baloxavir

Product purity: ≥ 98%

CAS No:1985605-59-1

Molecular formula: C24H19F2N3O4S

Molecular weight: 483.49

Detection method: HPLC

Active ingredient: Baroxavir

Product Description: White to light yellow oval shaped film coated sheet

Product Usage: Patients with influenza A and B

Product packaging: 20mg * 2 tablets/box

Product storage: 2-8 ℃

Shelf life: 24 months


Declaration of Use: This product is intended for industrial use or scientific research only.


Products Description  

Overview of Shaanxi Sunrise High-Purity Baloxavir ProductBaloxavir

Shaanxi Sunrise focuses on providing high-purity baloxavir raw materials that meet strict pharmaceutical standards. Our products undergo precise synthesis processes and strict multi-level quality control systems (including advanced analytical techniques such as HPLC, GC, and MS), ensuring that the purity of the main component of baloxavir remains stable at ≥99%, and the content of key impurities is far lower than those stipulated in the pharmacopoeia and customer-specific requirements. The quality and effectiveness of the raw materials fully comply with standards. The baloxavir we provide meets the core requirements as a drug active ingredient (API), aiming to provide reliable and compliant high-quality raw materials for downstream formulation manufacturers, and help develop safe and effective anti-influenza drugs.

 

Choosing Shaanxi Sunrise, you will obtain a trustworthy partner in terms of quality and supply stability.

 

Products Function

Balosevir is the active metabolite of the anti influenza drug Mabosevir (trade name: Sifluza), and its core efficacy is:

1. Targeted inhibition of virus replication

By specifically inhibiting the "cap dependent endonuclease" (CEN) of influenza virus, blocking virus mRNA synthesis, the virus genome cannot replicate

The mechanism of action is different from neuraminidase inhibitors such as oseltamivir, which directly achieve "source blocking" in the early stage of virus replication

2. Quickly reduce viral load

Clinical studies have shown that a single dose significantly reduces viral load within 24 hours and shortens the duration of influenza symptoms by about 1 day

3. Broad spectrum antiviral activity

Effective against influenza A (including H1N1, H3N2, and avian influenza H5N1/H7N9) and influenza B viruses

 

 

Products Aplication

Balosevir, as an active pharmaceutical ingredient, is mainly used in the manufacture of anti influenza drug Mabosevir formulations (tablets/suspensions), and its clinical applications include:

Scope of indications

Advantages of drug administration

Treatment of simple influenza A/B in adults and children aged ≥ 5 years (medication taken within 48 hours of symptom onset)

Suitable for high-risk populations with influenza complications (such as chronic disease patients, elderly people)

 

Single dose oral administration: only one dose is needed throughout the entire process, with high patient compliance

Half life of up to 79-125 hours, with longer lasting efficacy than traditional drugs

 

 

product comparison

The characteristics of balosavir and other anti influenza drugs:

Characteristics

Balosavir

Oseltamivir

Mechanism of action

Cap dependent endonuclease inhibitor

Neuraminidase inhibitor

Medication regimen

Single oral dose

Twice daily for 5 consecutive days

Effective time

Within 24 hours

24-48 hours

Half life

79-125 hours

6-10 hours

Drug resistance

There is a risk of drug resistance

Some strains are resistant

 

 

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