5-Hydroxytryptophan 98% Powder

5-Hydroxytryptophan, 5-HTP 98% powder, CAS 56-69-9, Griffonia Simplicifolia extract, natural anti-stress API, skin calming botanical, neuro-cosmetic extract, grayish-white powder, bulk 5-HTP wholesale

Factory supply 98% purity 5-Hydroxytryptophan (5-HTP) powder CAS 56-69-9 from Griffonia Simplicifolia seeds. Premium natural API for skin calming, barrier defense, and anti-stress cosmetic formulas.



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Description



✓ cGMP Standard Botanical Extract Supplier            ✓ ISO 9001:2015 Certified Facility            ✓ Third-Party Lab Verified
Origin: Factory Direct Manufacturer

5-Hydroxytryptophan 98% Bulk Supply

Custom Botanical Extraction • High-Purity Natural Anti-Stress Active

⚠            Declaration:            This product is industrial cosmetic and nutritional raw material only, not finished retail goods. All formula development must be completed by professional R&D technicians.
                   5-Hydroxytryptophan 98% 2                    
5-Hydroxytryptophan 98% 1      5-Hydroxytryptophan 98% 35-Hydroxytryptophan 98% 4

Standardized ≥98% Purity via HPLC Verification

CAS No.56-69-9
Purity (HPLC)≥ 98.0%
Molecular FormulaC11H12N2O3
Molecular Weight220.23 Da
Botanical SourceGriffonia Simplicifolia Seed
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Scientific Overview & Manufacturing Excellence

We specialize in the contract manufacturing and stable bulk supply of 98% 5-Hydroxytryptophan (5-HTP), a highly advanced natural amino acid compound meticulously extracted and refined from premium Griffonia Simplicifolia seeds. Emerging as a revolutionary neuro-cosmetic active globally, 5-HTP functions by addressing the skin's neuro-receptors to profoundly calm localized stress, ease uncomfortable tightness, and restore the skin barrier's natural resilience against environmental aggressors.

Our facility utilizes state-of-the-art multi-stage botanical extraction and precision crystallization technologies to isolate this specific precursor molecule. The finished product is a uniform grayish-white powder characterized by excellent biological bioavailability and stability. All production processes are executed in GMP-standard dust-free workshops with full ISO9001 certification and complete batch traceability, ensuring a strict ≥98.0% purity index via precise HPLC detection, entirely free from unrefined plant fibers or solvent residues.

Target Application Scenarios & Formulation Benefits

Our 98% HPLC-grade 5-Hydroxytryptophan complies with stringent international cosmetic and nutritional raw material safety regulations. Its multi-target restorative profile makes it widely utilized in:

  • ✔ Anti-Stress & Redness Relief: Acts as a powerful neuro-calming agent for the skin. It rapidly eases feelings of tightness, significantly calms environmentally stressed skin, and provides lasting relief from localized redness.

  • ✔ Barrier Defense & Tolerance: Strengthens the skin's intrinsic defense mechanisms against external pollutants and harsh climates. By reducing reactivity to external irritation, it systematically improves overall skin tolerance over time.

  • ✔ Moisturization & Smoothing: Actively supports the hydration of the skin's surface layer. It effectively improves chronic dryness and structural roughness, resulting in a noticeably softer, more supple epidermal texture.

Technical Specifications & Logistics Standard

Product Identity5-Hydroxytryptophan / 5-HTP (Skin Calming API)
Botanical SourceStandardized Griffonia Simplicifolia Seed Extract
Testing Method & PurityHPLC Analysis; ≥ 98.0% Monomer
Physicochemical Properties• Appearance: Grayish-white powder
                           • Moisture: ≤ 5.0%
                           • Ash Content: ≤ 2.0%
                           • Solubility: Slightly soluble in water; soluble in hot aqueous-glycol or ethanol systems
Heavy Metals & SafetyHeavy Metal (Pb) ≤10ppm; Arsenic (As) ≤2ppm. Compliant with EU & FDA safety standards.
Packaging Configurations• Sample Scale: 1kg vacuum light-proof aluminum foil bag
                           • Bulk Commercial: 25kg sealed export fiber drum
                           *Private label branding and custom trial specs available.
Storage & Shelf LifeStore sealed in a cool, dry & dark environment. Validity is 24 months.

Precautions & Formulation Guidelines

  • Solubility Profile: 5-Hydroxytryptophan is only slightly soluble in cold water. For seamless integration into cosmetic formulations, pre-dissolve the powder in a warm aqueous-glycol system (e.g., using propanediol or butylene glycol) before adding to the main emulsion.

  • Color Consideration: The naturally occurring grayish-white hue of the pure extract will not significantly tint final formulations at standard clinical dosages (typically 0.1% to 1.0%), making it suitable for white creams and translucent serums.

  • Compatibility Suggestion: It demonstrates outstanding formulation synergy when combined with other barrier-restoring or soothing agents (such as Ceramides, Panthenol, or Bisabolol) to create premium "anti-stress" or "neuro-calming" skincare lines.

  • Storage Notice: Keep tightly sealed after opening. Ensure storage away from strong light and moisture to prevent oxidation and maintain the integrity of the amino acid structure.

Frequently Asked Questions (Procurement & Formulation)

Why extract 5-HTP from Griffonia Simplicifolia seeds instead of synthesizing it?
Griffonia Simplicifolia seeds are one of the most abundant natural sources of 5-Hydroxytryptophan in the botanical world. Extracting it directly from these seeds yields a highly bio-compatible, sustainable, and natural amino acid compound, meeting the growing consumer demand for clean-label, plant-derived cosmetic ingredients without the use of harsh synthetic pathways.
How does 5-HTP calm stressed skin?
5-HTP acts as a neuro-cosmetic agent. It helps modulate the cutaneous nervous system's response to environmental aggressors. By soothing hypersensitive nerve endings in the epidermis, it rapidly reduces physical sensations of tightness and irritation, subsequently diminishing the visible signs of stress-induced redness.
Will the grayish-white color affect my final cosmetic formula?
No. The 98% purity ensures that inactive plant chromophores are removed. When used at the recommended formulation dosages (usually between 0.1% and 1.0%), the fine grayish-white powder dissolves cleanly and will not impart a noticeable tint or discolor your final white creams or transparent serums.
Do you supply finished cosmetic creams or retail soothing serums?
No. We are strictly an upstream B2B raw material manufacturer and supplier. We provide bulk 5-HTP 98% powder to empower pharmaceutical companies, cosmetic brands, and laboratories to manufacture their own retail products. We do not sell finished retail formulations.
Can you provide samples and complete test certificates for customs clearance?
Yes, we provide sample testing for quality and formulation verification for qualified B2B buyers. Each commercial bulk order comes with an official Certificate of Analysis (COA) specifying HPLC test results, commercial invoice, packing list, and MSDS to ensure smooth global customs clearance and product filing.

Shaanxi Sunrise Pharmaceutical Co., Ltd.

Senior Independent Site Operations Specialist: Betty

📧 Email: betty@pharma-sunrise.com            💬 WhatsApp: +86 18092760627