Afatinib API CAS No: 439081-18-2
Afatinib API CAS No: 439081-18-2,Afatinib API ,CAS No: 439081-18-2,Afatinib
Content
Product Introduction
 | Product Name: Afatinib API Product Purity: ≥98% CAS No: 439081-18-2 Molecular Formula: C₂₄H₂₅ClFN₅O₃ Declaration of Use: This product is intended for industrial use or scientific research only. |
Products Description
We specialise in the production of high-purity Afatinib active pharmaceutical ingredient (API). The product presents as a white or off-white crystalline powder with a stable purity of ≥98%, meeting stringent pharmaceutical raw material quality standards. Manufactured via synthetic processes, it undergoes rigorous quality control via HPLC analysis with clearly defined core constituents. We offer industrial packaging in 1kg aluminium foil bags and 25kg drums. The product maintains stability for 24 months when stored in a cool, dry, and light-protected environment, with refrigeration at 2-8°C recommended for optimal long-term stability throughout the supply chain.
Our product adheres strictly to high-standard manufacturing protocols, designed to meet the rigorous requirements of pharmaceutical formulation research and production. High-quality Afatinib API forms the foundation for ensuring the efficacy, safety, and consistency of subsequent formulations. We are committed to providing reliable, compliant active pharmaceutical ingredients, serving as your trusted supply chain partner.
Unique Advantages
• High Purity & Consistency: Guaranteed purity of ≥98%, ensuring reliable performance and compliance for pharmaceutical formulations.
• Stringent Quality Control: Production and testing adhere to rigorous standards, with HPLC methodology employed for precise quality verification.
• Proven Stability: Offered with a 24-month shelf life under recommended storage conditions (cool, dry, and protected from light, ideally 2-8°C), ensuring integrity throughout the supply chain.
• Industrial-Scale Supply: Available in commercial quantities (1kg & 25kg packaging), supported by a robust and reliable manufacturing process.
Product Function
This product functions as the high-quality Active Pharmaceutical Ingredient (API) for Afatinib, a targeted therapy drug. It is supplied as a white to off-white crystalline powder, serving as the core active component in the final pharmaceutical dosage form.
Product Application
Primarily used in the pharmaceutical industry for the formulation and manufacturing of finished dosage forms, such as tablets, indicated for the treatment of specific types of non-small cell lung cancer (NSCLC).
Mechanism of Action
Afatinib is a second-generation, irreversible inhibitor of the ErbB family of tyrosine kinases. It covalently binds to and blocks the signaling of Epidermal Growth Factor Receptor (EGFR) and Human Epidermal Growth Factor Receptor 2 (HER2), which are often dysregulated in certain cancers, thereby inhibiting tumor cell proliferation and survival.