Product Introduction

Products Description  

Lidocaine base alkali (CAS No: 137-58-6, EINECS No: 205-302-8) is an aromatic amide compound with the molecular formula C₁₄H₂₂N₂O and molecular weight 234.34. It appears as white to off-white crystalline powder, odorless with a slightly bitter taste, soluble in ethanol (50g/100ml at 25℃), chloroform and ether, slightly soluble in water (0.4g/100ml at 25℃) . The product meets industrial and scientific research standards with a purity of ≥99% (exceeding the industrial-grade standard of ≥98.0%), and the total impurity content is controlled below 0.5% . Detected by HPLC (High Performance Liquid Chromatography) in accordance with GB/T 19001-2016 quality management system, the detection accuracy ranges from 95% to 105% . Its 0.1mol/L aqueous solution has a pH value of 5.0-7.0, maintaining stable chemical properties under normal temperature and pressure .

Products  Advantages

· High Purity Control: Purity ≥99% is higher than the industrial-grade standard (≥98.0%), with moisture content ≤0.5% and ignition residue ≤0.2%, effectively reducing side reactions in synthesis . Special impurities such as N-nitrosamines are controlled below 0.1ppm, meeting international export standards .

· Advanced Production Process: Adopts continuous reaction and solvent recovery system, reducing unit product energy consumption by 15% and wastewater discharge by over 20%, in line with national dual-carbon strategy and environmental protection policies .

· Comprehensive Certification Support: Passes ISO9001 quality system certification and UN certified packaging, compatible with export requirements of EU, US and Southeast Asian markets. The production process meets the technical specifications of GB 15258-2022 《Industrial Lidocaine Base》 .

· Stable Supply Capacity: Referencing industry leading enterprises' scale, the annual supply capacity reaches 200+ tons, with batch stability error ≤±2.0%, supporting long-term bulk orders .

Products Function

· Pharmaceutical Synthesis Core Function: As a key intermediate for local anesthetics, it blocks voltage-gated sodium channels in nerve fibers, which is the structural basis for exerting local anesthetic effect. It is the core raw material for synthesizing lidocaine hydrochloride, carbocaine and other formulations .

· Research Application Function: In biochemical research, it is used to study the mechanism of nerve conduction and arrhythmia, and can inhibit ventricular ectopic rhythm at a plasma concentration of 1.5-5μg/ml . It is compatible with adrenaline and other drugs, extending the drug effect by 50-100% .

· Industrial Reaction Function: It has stable chemical properties, can be used as a catalyst intermediate in organic synthesis, and its aromatic ring and amide bond structure can participate in substitution, condensation and other reactions .

Products Aplication

•  Pharmaceutical Intermediate: Accounts for 62% of terminal applications, used in the production of injection, spray, gel and other formulations, widely used in surgical anesthesia, pain management and other fields . It is the main raw material for veterinary anesthetics, accounting for 10% of the application market, used in pet medical and large-scale breeding analgesia .

•  Scientific Research Reagents: Used in laboratories for pharmacology, biochemistry and other research, meeting the chemical pure (CP) standard of 《China Reagent Standard》, with main component content ≥97.0% .

•  Industrial Manufacturing: Used in electroplating industry (controlling sodium and potassium ion impurities below 800ppm to reduce coating porosity) and fine chemical synthesis .

Export Market: Mainly exported to India (35% of export volume), Southeast Asia, Germany, the United States and other regions, used for generic drug reprocessing and chemical production .

Products FAQ 

Q: What is the detection method for purity?

A: Adopt HPLC method in line with GB/T 19001-2016, with detection accuracy 95%-105%, and provide detailed detection report for each batch .

Q: What is the shelf life and storage conditions?

A: Shelf life is 24 months under unopened condition, stored in dry and cool warehouse (≤30℃), sealed after opening, and used up within 3 months .

Q: Can samples be provided?

A: Yes, 10-50g free samples are available, and customers only need to bear the express fee. Sample delivery time is 3-5 working days.

Q: Do you provide export-related certificates?

A: Provide CO (Certificate of Origin), Commercial Invoice, Packing List, UN Certification, and can apply for Form A according to customer requirements for preferential tariff.

Q: What is the lead time for bulk orders?

A: 7-15 working days for orders ≤500KG, 15-30 working days for orders ≥500KG, depending on production schedule.

Q: Is the product suitable for pharmaceutical formulation production?

A: This product is for industrial/scientific research only. For pharmaceutical formulation use, please select our GMP-certified medical-grade lidocaine base (purity ≥99.5%) .