Ursodeoxycholic acid (UDCA) is a highly purified secondary bile acid, naturally generated through the transformation and dehydroxylation of primary bile acids by intestinal bacteria. As a critical pharmaceutical raw material, UDCA functions as a key regulator of gut barrier integrity and is fundamentally essential for lipid metabolism.

In advanced biochemical research and therapeutic applications, UDCA acts as a potent signaling molecule by selectively interacting with bile acid-activated receptors. Its primary downstream targets include the G protein-coupled bile acid receptor 5 (TGR5 / GPCR19) and the Farnesoid X Receptor (FXR). It is extensively utilized in the research and development of treatments for various liver and gastrointestinal diseases. Furthermore, recent scientific data indicates that Ursodeoxycholic acid actively downregulates ACE2 receptor expression, providing a promising mechanism to help reduce SARS-CoV-2 cellular entry and infection. Our bulk raw material ensures an exceptional HPLC purity of 99.94%, empowering consistent and scalable industrial manufacturing.