Lumbrokinase Peptide ≥75% (Pheretima aspergillum): A Sourcing Guide for Cardiovascular Formulations
Written from the perspective of an operations specialist and raw-material supplier in the bioactive peptide trade. This is general technical guidance for procurement and R&D teams. It is not medical advice; fibrinolytic and cardiovascular claims are regulated and must be handled carefully.
Among cardiovascular-ingredient suppliers, the word "lumbrokinase" usually gets attention fast — and then a long pause. It is an enzyme peptide with genuine fibrinolytic activity, sourced from a non-obvious place (the earthworm), and it is easy to either overstate or understate on a datasheet. The professional job is to separate the biochemistry from the marketing.
This is the sheet I walk buyers through on the operations side. It is written for procurement and R&D teams evaluating cardiovascular peptide suppliers, and it applies whoever you finally buy from.
What "lumbrokinase peptide ≥75%" means on a datasheet
Lumbrokinase Peptide is a high-purity bioactive small-molecule peptide refined from Pheretima aspergillum (earthworm). The key technical lines are:
Specification: ≥75% peptide content
Biological source: Pheretima aspergillum (earthworm)
Core bioactive property: natural fibrinolytic enzymes & active proteases
Processing: low-temperature biological enzymatic hydrolysis & membrane separation
Appearance / shelf life: light-brown fine powder | 24 months
The line to read carefully is the bioactive property, not just the purity. This ingredient carries natural fibrinolytic enzyme activity, which is why it is researched for cardiovascular-support and blood-microcirculation formulations — and why, precisely because of that activity, the surrounding claims need strict handling.
Why a purified peptide form beats crude earthworm powder
| Characteristic | What it means in formulation |
|---|---|
| Concentrated activity | Retains stable fibrinolytic enzyme activity instead of the variability of crude powder. |
| Odor & impurity removal | Hydrolysis and membrane separation remove insoluble impurities and peculiar odors. |
| Bioavailability | Small-molecule peptide structure avoids digestive barriers for faster functional expression. |
| Processing-friendly | Low moisture and good fluidity suit capsules, tableting and powder blending. |
| Blend compatibility | Compatible with nattokinase, red yeast rice extract, taurine and plant flavonoids. |
"Cardiovascular support," "fibrinolytic" and "microcirculation" are regulated, health-adjacent terms in most markets. On a B2B datasheet they describe the intended raw-material direction; they must never be copied onto consumer packaging without a full regulatory review of the finished product.
What to verify before you buy
Purity and source. Confirm the ≥75% peptide specification and the biological source Pheretima aspergillum.
Enzyme activity, not just protein. Because this is a fibrinolytic enzyme peptide, ask for an activity test report — "peptide content" and "active fibrinolytic activity" are different things and both belong on the COA.
Clean extraction. Confirm physical and biological processing with no chemical-solvent residue if that matters for your market.
Batch documentation. COA, fibrinolytic activity test report, and MSDS for shipping and filing.
Our production runs in an ISO 9001:2015-certified facility with GMP-aligned controls and third-party lab verification — but the same four questions should be asked of any candidate supplier.
Where formulators use ≥75% lumbrokinase peptide
Cardiovascular dietary supplements — vascular-conditioning capsules, fibrinolytic health tablets and daily cardiovascular-maintenance formulas.
Compound microcirculation blends — synergistic formulas combining nattokinase, red yeast rice extract, taurine and plant flavonoids.
High-bioavailability concepts — where a small-molecule enzyme peptide is needed rather than crude protein.
Custom R&D — as a targeted fibrinolytic active base for contract manufacturing.
A quick supplier qualification checklist
Verify the entity and role. Manufacturer vs. trader, matched to your contract.
Confirm purity, biological source and process. ≥75% peptide, Pheretima aspergillum, and hydrolysis / membrane separation.
Request the fibrinolytic activity test report alongside the COA — activity is the meaningful specification here.
Review regulatory positioning for your target market before drafting any consumer claims.
Check packaging and logistics. 1 kg foil bags and 25 kg export fiber drums, with in-stock sample shipping in roughly 1–3 days.
If you would like to compare this cardiovascular peptide with our other peptide ingredients, the SR-Peptides category is the place to start, with the full catalogue under Products and company background on the About Us page.
Frequently asked questions
What is the advantage over ordinary earthworm powder?
Ordinary earthworm powder contains macromolecular proteins, insoluble impurities and unpleasant odors, with unstable fibrinolytic activity. Lumbrokinase Peptide ≥75% is purified to retain high-activity fibrinolytic small-molecule peptides with better stability and bioavailability.
What are the main functions of Pheretima aspergillum lumbrokinase peptide?
It is rich in natural fibrinolytic enzymes and active proteases, positioned to support cardiovascular health, assist microcirculation regulation and improve blood fluidity — framed here as raw-material direction, not a consumer medical claim.
Do you supply finished cardiovascular supplement capsules or retail products?
No. We are strictly an upstream B2B raw-material manufacturer and supply bulk Lumbrokinase Peptide ≥75% powder to supplement brands, food factories and research labs; we do not sell finished retail formulations.
Is this earthworm-derived peptide safe for long-term addition?
It is extracted from natural Pheretima aspergillum via low-temperature biological and physical technology without chemical solvent residues or hormones, and is positioned as food-grade for qualified daily health-care products. Suitability for long-term use must be confirmed in your finished formulation and market rules.
Can you provide complete activity test reports for customs clearance?
Yes. Free sample testing is available, and each commercial bulk order includes a COA, fibrinolytic activity test report, commercial invoice, packing list and MSDS for customs clearance and filing.
Intended-use statement. This product is sold as a raw material for formulating finished foods and dietary supplements. It is not intended to diagnose, treat, cure or prevent any disease. Because it carries fibrinolytic enzyme activity, finished-product claims, dosage and any interaction considerations must be evaluated by qualified professionals against the regulations of the target market.