98% Baicalein Powder CAS 491-67-8 | Botanical Extract Supplier

98% baicalein powder,scutellaria root baicalein,baicalein antioxidant raw material,baicalein soothing cosmetic ingredient,HPLC tested baicalein,bulk baicalein flavonoid monomer

Source high-purity 98% Baicalein orange-yellow needle crystals (CAS 491-67-8) directly from cGMP manufacturer. HPLC verified botanical extract for cosmetic & nutraceutical R&D

Send Inquiry
Description

Baicalein 98% Bulk Supply

Custom Botanical Extraction • High-Purity Flavonoid Monomer
Declaration: This product is intended for industrial functional formulation and scientific research only. Not a finished medicine or skincare product.
cGMP STANDARD BOTANICAL EXTRACT SUPPLIER

Baicalein 98%

CAS No.: 491-67-8

Purity (HPLC)≥ 98.0%
Molecular FormulaC15H10O5
Molecular Weight270.24 Da
Botanical SourceScutellaria Root (S. baicalensis)
💡 Quick Connection Notice: If your email link doesn't open, please directly send inquiries to: betty@pharma-sunrise.com

Scientific Overview & Manufacturing Excellence

We specialize in the advanced botanical extraction and mass bulk supply of 98% Baicalein, a high-purity natural flavonoid monomer refined from premium dried scutellaria root (Scutellaria baicalensis). Through sophisticated multi-stage water extraction, macroporous resin separation, and low-temperature recrystallization purification technology, we produce uniform orange-yellow needle-like crystals.

The entire production workflow utilizes a pure physical purification process within our 100,000-class GMP dust-free closed workshops, ensuring full batch quality traceability. Every single batch is strictly calibrated via High-Performance Liquid Chromatography (HPLC) to guarantee a stable 98% monomer purity. We supply stable, low-impurity compliant raw materials for global cosmetic factories, health supplement brands, and biomedical research institutions.

Core Functions & Pharmacological Mechanisms

Powerful Antioxidant & Anti-aging

Baicalein efficiently clears excess free radicals inside the skin and cells. By reducing oxidative damage to tissues, it effectively delays cellular aging and fades dull complexions, offering superior antioxidant capacity compared to mixed botanical extracts.

Anti-inflammatory & Sensitive Soothing

As a targeted natural flavonoid, it suppresses the release of inflammatory mediators. It rapidly relieves facial redness, stinging, and sensitive discomfort caused by external stimulation, simultaneously helping to repair a fragile or compromised skin barrier.

Metabolic Regulation & Cardiovascular Protection

Applicable to oral health formulas, Baicalein optimizes human metabolic circulation and helps maintain vascular elasticity. It assists in stabilizing lipid levels and enhances the body's self-resistance to keep physical functions balanced and stable.

Target Application Scenarios & Formulation Objectives

Sensitive Soothing Skincare

Ideal for integrating into redness relief essences, barrier repair creams, anti-allergy toners, and intensive post-sun repair lotions.

Cardiovascular Health Supplements

Core active ingredient for lipid balance nutritional powders, oral anti-oxidation solid drinks, and daily metabolic conditioning herbal tablets.

Biomedical Laboratory Research

Deployed as a highly purified natural flavonoid standard reference substance and a reliable reagent for anti-inflammatory cell experiments.

Technical Specifications & Quality Standards

Product IdentityBaicalein (Natural Flavonoid Monomer API)
Botanical SourcePremium Scutellaria Root (Scutellaria baicalensis)
Testing Method & PurityHPLC Analysis; ≥ 98.0% Monomer
Physicochemical Properties• Appearance: Orange-yellow Needle-like Crystals
• Moisture: ≤ 5.0%
• Ash Content: ≤ 4.0%
• Mesh Size: 80-100 Mesh
Heavy Metals & SafetyHeavy Metal (Pb) ≤10ppm; Arsenic (As) ≤2ppm. Compliant with FDA/EU/GB safety standards. Low residual solvent.
Packaging Configurations• Sample Scale: 1kg vacuum light-proof aluminum foil bag
• Bulk Commercial: 25kg sealed light-blocking fiber drum
*Private label and custom small batch specs available.
Storage & Shelf LifeStore sealed in a cool, dry & dark environment. Avoid high temperature & strong light. Validity is 24 months.

Precautions & Formulation Guidelines

  • Light Sensitivity Storage: Baicalein crystal is highly sensitive to strong light. Long-term light exposure will cause discoloration and active degradation; it must be fully sealed and stored in a dark environment.

  • Solubility Matching: Slightly soluble in water, but easily soluble in ethanol, propylene glycol, and glycerin. Aqueous formulations require appropriate polyol cosolvents to prevent precipitation.

  • Production Operation Protection: Personnel must wear dust-proof masks and gloves during weighing and feeding to prevent respiratory and skin contact irritation from the fine crystal powder.

  • Formula pH Adaptation: The optimal formula pH range is 4.5–7.5. A strong alkaline environment will destroy the flavonoid structure and severely reduce its biological efficacy.

  • Compatibility Reminder: Avoid simultaneous matching with high-concentration oxidants in a formula, as this will prematurely consume the antioxidant activity of Baicalein.

  • Transportation Protection: Packaging must be strictly moisture-proof and light-proof. Prevent extrusion or impact damage that could lead to crystal leakage and compromised seal integrity.

  • Target Crowd Reference: Oral formulas intended for pregnant women and infants require thorough safety stability testing prior to mass commercial production.

Frequently Asked Questions (Procurement & Quality)

What is the difference between baicalein and scutellaria root total extract?

98% baicalein is a highly purified single flavonoid monomer tested by HPLC, boasting targeted anti-inflammatory and antioxidant efficacy. Scutellaria total extract is a mixed flavonoid blend with low single-ingredient content, typically utilized for mass-market, lower-cost health products.

Is baicalein easy to precipitate in water-based skincare?

It is slightly soluble in pure water. For water-based serum or toner formulations, adding 5%-10% propylene glycol or glycerin as a cosolvent can significantly improve its solubility and avoid crystallization or precipitation.

Why must baicalein be strictly stored away from light?

The Baicalein flavonoid molecular structure is photosensitive. Long-term exposure to ultraviolet and strong ambient light will lead to crystal darkening (discoloration) and a significant decline in its antioxidant and anti-inflammatory biological activity.

Can you supply complete registration documents for overseas cosmetics and health food?

Yes. With extensive global export experience supplying overseas beauty brands and health food factories, we provide a full set of HPLC chromatogram reports, COAs, MSDS, and heavy metal & microbial inspection certificates to fully support your brand filing and customs clearance.

Shaanxi Sunrise Pharmaceutical Co., Ltd.

Senior Independent Site Operations Specialist: Betty

📧 Email: betty@pharma-sunrise.com|💬 WhatsApp: +86 18092760627