Product Introduction
Product Name: Cetrorelix Acetate
Product Purity: ≥98% (Research Grade)
CAS No: 120287-85-6
Testing Method: HPLC (High Performance Liquid Chromatography)
Active Ingredient: Cetrorelix Acetate
Product Characteristics: White to off-white powder
Product Mesh: 80-120 mesh
Product Use: Only for laboratory-level reproductive medicine research, endocrine mechanism research, and drug development-related studies (not for human/animal use)
Storage Conditions: Light shielded, sealed, refrigerated at 2-8°C (strictly prohibited from freezing)
Shelf Life: 2-3 years (unopened, specific period as indicated on packaging)
Product Description & Research Information
Cetrorelix Acetate is a synthetic gonadotropin-releasing hormone (GnRH) antagonist, chemically classified as a cyclic decapeptide derivative. Our research-grade product is manufactured to a purity of ≥98% (HPLC verified), ensuring high quality for your sensitive laboratory assays.
In research settings, this compound is known to competitively bind to GnRH receptors in pituitary cell models, inhibiting the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in a dose-dependent manner. This mechanism makes it a valuable tool for studying the hypothalamic-pituitary-gonadal (HPG) axis and reproductive hormone regulation in in vitro or ex vivo research systems.
Research-Oriented Mechanism of Action Reference
The following information is derived from public academic literature, only for laboratory research background reference:
GnRH Receptor Antagonism: Competitively binds to and blocks GnRH receptors in pituitary cell lines, leading to rapid suppression of LH and FSH secretion.
Reproductive Axis Modulation: Its suppressive effect on gonadotropin release is reversible upon discontinuation in research models.
Research Application Scenarios (Laboratory Only)
| Research Direction | Research Value Reference |
|---|---|
| GnRH Receptor Pharmacology | Study binding kinetics and signaling pathways of GnRH receptors in transfected cell lines. |
| Reproductive Endocrinology | Investigate the role of LH and FSH in folliculogenesis using in vitro ovarian models. |
| Assisted Reproductive Technology (ART) Research | Study effects of LH surge inhibition on oocyte maturation in animal models. |
| Oncology Research | Evaluate potential as an anti-cancer agent in hormone-sensitive cancer models. |
Core Advantages
High Purity & Quality: ≥98% (HPLC verified) for reliable bioassays.
Well-Characterized Compound: A widely cited GnRH antagonist in reproductive research.
Flexible Packaging: Customizable lyophilized powder sizes for diverse research needs.
Stability & Long Shelf-Life: 2-3 years shelf life when stored correctly.
Comprehensive Documentation: Detailed Certificate of Analysis (COA) provided.
FAQ (For Research Use Only)
Q1: How to obtain the COA quality inspection report?
A: Contact our customer service with your order number to obtain the electronic COA, or verify it through our official website's portal.
Q2: Does this product support customization?
A: Yes, we offer customization for purity, packaging, and dosage. Contact customer service for details; customized products also include a COA.
Q3: What are the procurement subject requirements?
A: Only supplied to legal research institutions (pharmaceutical R&D companies, biotech labs, universities). Individuals are not eligible. Qualification documents are required.
Q4: What makes Cetrorelix Acetate valuable in reproductive research?
A: As a potent and reversible GnRH antagonist, it allows precise and temporary blocking of the HPG axis in models, making it crucial for studying follicle development, ovulation, and infertility mechanisms.